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BIOLOGICAL AGENTS

Biological terrorism is the use of microorganisms or toxins derived from living organisms to produce death or disease in humans, animals, or plants. Some biologic agents can serve dual purposes: Botulinum toxin, for example, has several therapeutic uses, including the treatment of certain neuromuscular disorders.

Recent events have demonstrated the vulnerability of civilian populations to the threat of biological agents. The following disease agents are believed to have the greatest potential for bioterrorism:

  • Anthrax
  • Tularemia
  • Plague
  • Smallpox
  • Botulinum toxins
  • Viral hemorrhagic fevers, such as Ebola and Marburg
  • Cutaneous Anthrax


Cutaneous Anthrax

Routes of Exposure

Inhalation
The route of exposure of most concern with biological terrorist attacks is inhalation of the agent. In an attack, a terrorist might attempt to generate aerosols of the biological agent, which would produce particles of the right size and diameter to be inhaled deeply into the lungs where they would begin to cause illness. The aerosol could be odorless, colorless, and invisible due to its small particle size. Inhalation was the route of exposure that caused deaths during the anthrax mail attacks in the United States in the fall of 2001.

Oral
Oral routes of exposure for biological agents are believed less important, but are still significant. Contamination may occur directly or secondarily after an aerosol attack and may represent a hazard for infection or intoxication by ingestion. Ensuring that the food and water supply is free of contamination is an important function of public health and should be done as soon as possible after a
biological attack.

Dermal
Intact skin provides the most effective barrier for many, but not all, biological agents. Mucous membranes and abraded or otherwise damaged skin can allow passage of some bacteria and viruses: these areas should be protected in the event of an attack.

Responding to a Biological Attack  

 
  
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